K-RAS anticorps (AA 1-188)

N° du produit ABIN561621

Cet anticorps anti-K-RAS est un anticorps Souris Monoclonal détectant K-RAS dans WB, ELISA et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 5+ publications.

Aperçu rapide pour K-RAS anticorps (AA 1-188) (ABIN561621)

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp K-RAS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3B10-2F2

Détail du produit anti-K-RAS anticorps

Épitope: AA 1-188

Fonction: Mouse monoclonal antibody raised against a full length recombinant KRAS.

Séquence: MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-K-RAS (ABIN561621)

Madureira, Bharadwaj, Bydoun, Garant, OConnell, Lee, Waisman: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." dans: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).

King, Bray, Galbraith, Christie, Fleming: "Evidence for aldosterone-dependent growth of renal cell carcinoma." dans: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).

Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." dans: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

Valtorta, Misale, Sartore-Bianchi, Nagtegaal, Paraf, Lauricella, Dimartino, Hobor, Jacobs, Ercolani, Lamba, Scala, Veronese, Laurent-Puig, Siena, Tejpar, Mottolese, Punt, Gambacorta, Bardelli et al.: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." dans: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).

Fuentes-Calvo, Blázquez-Medela, Santos, López-Novoa, Martínez-Salgado: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." dans: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).

Détails sur K-RAS

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS

Sujet: Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2

ID gène: 3845