LETM1 anticorps (AA 601-708)

N° du produit ABIN561659

L’anticorps Souris Monoclonal anti-LETM1 a été validé pour WB, ELISA, IF, IP et IHC (p). Il convient pour détecter LETM1 dans des échantillons de Humain. Il y a 6+ publications disponibles.

Aperçu rapide pour LETM1 anticorps (AA 601-708) (ABIN561659)

Antigène: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LETM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6F7

Détail du produit anti-LETM1 anticorps

Épitope: AA 601-708

Fonction: Mouse monoclonal antibody raised against a partial recombinant LETM1.

Séquence: ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVA

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: LETM1 (NP_036450, 601 a.a. ~ 708 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-LETM1 (ABIN561659)

Chen, Yang, Liu, Piao, Zhang, Lin, Li: "High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma." dans: BioMed research international, Vol. 2014, pp. 850316, (2014) (PubMed).

Doonan, Chandramoorthy, Hoffman, Zhang, Cárdenas, Shanmughapriya, Rajan, Vallem, Chen, Foskett, Cheung, Houser, Madesh: "LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4936-49, (2014) (PubMed).

Shin, Chung, Kang, Jiang, Yu, Han, Chae, Moon, Jang, Cho: "Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice." dans: Cancer gene therapy, Vol. 20, Issue 3, pp. 186-94, (2013) (PubMed).

Piao, Li, Kim, Sohn, Yang, Park, Byun, Won, Hong, Hur, Seok, Shong, Sack, Brazil, Hemmings, Park: "Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis." dans: Cellular signalling, Vol. 21, Issue 5, pp. 767-77, (2009) (PubMed).

Piao, Li, Kim, Byun, Huang, Hwang, Yang, Park, Won, Hong, Hur, Seok, Shong, Cho, Brazil, Hemmings, Park: "Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death." dans: Cancer research, Vol. 69, Issue 8, pp. 3397-404, (2009) (PubMed).

Dimmer, Navoni, Casarin, Trevisson, Endele, Winterpacht, Salviati, Scorrano: "LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability." dans: Human molecular genetics, Vol. 17, Issue 2, pp. 201-14, (2008) (PubMed).

Détails sur LETM1

Antigène: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Autre désignation: LETM1

Sujet: Full Gene Name: leucine zipper-EF-hand containing transmembrane protein 1
Synonyms:

ID gène: 3954

NCBI Accession: NM_012318