RAB27A anticorps (AA 122-221)

N° du produit ABIN562560

Cet anticorps anti-RAB27A est un anticorps Souris Monoclonal détectant RAB27A dans WB, ELISA, IHC (p) et RNAi. Adapté pour Humain. Ce Primary Antibody a été cité dans 8+ publications.

Aperçu rapide pour RAB27A anticorps (AA 122-221) (ABIN562560)

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAB27A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Clone: 1G7

Détail du produit anti-RAB27A anticorps

Épitope: AA 122-221

Fonction: Mouse monoclonal antibody raised against a partial recombinant RAB27A.

Séquence: YCENPDIVLC GNKSDLEDQR VVKEEEAIAL AEKYGIPYFE TSAANGTNIS QAIEMLLDLI MKRMERCVDK SWIPEGVVRS NGHASTDQLS EEKEKGACGC

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RAB27A (ABIN562560)

Felicetti, De Feo, Coscia, Puglisi, Pedini, Pasquini, Bellenghi, Errico, Pagani, Carè: "Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." dans: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).

Hannafon, Carpenter, Berry, Janknecht, Dooley, Ding: "Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)." dans: Molecular cancer, Vol. 14, pp. 133, (2015) (PubMed).

Cetica, Hackmann, Grieve, Sieni, Ciambotti, Coniglio, Pende, Gilmour, Romagnoli, Griffiths, Aricò: "Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding." dans: The Journal of allergy and clinical immunology, (2014) (PubMed).

Kimura, Yamaoka, Taniguchi, Okamoto, Takei, Ando, Iwamatsu, Watanabe, Kaibuchi, Ishizaki, Niki: "Activated Cdc42-bound IQGAP1 determines the cellular endocytic site." dans: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4834-43, (2013) (PubMed).

Peinado, Ale?kovi?, Lavotshkin, Matei, Costa-Silva, Moreno-Bueno, Hergueta-Redondo, Williams, García-Santos, Ghajar, Nitadori-Hoshino, Hoffman, Badal, Garcia, Callahan, Yuan, Martins, Skog, Kaplan et al.: "Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. ..." dans: Nature medicine, Vol. 18, Issue 6, pp. 883-91, (2012) (PubMed).

Sanchez-Ruiz, Valitutti, Dupre: "Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27057, (2011) (PubMed).

Neumüller, Hoffmeister, Babica, Prelle, Gegenbauer, Smolenski: "Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets." dans: Blood, Vol. 114, Issue 7, pp. 1396-404, (2009) (PubMed).

Kimura, Kaneko, Yamada, Ishihara, Senda, Iwamatsu, Niki: "The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines." dans: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3092-8, (2008) (PubMed).

Détails sur RAB27A

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Autre désignation: RAB27A

Sujet: Full Gene Name: RAB27A, member RAS oncogene family
Synonyms: GS2,HsT18676,MGC117246,RAB27,RAM

ID gène: 5873

NCBI Accession: NM_004580

Pathways: Peptide Hormone Metabolism