RRM2 anticorps (AA 1-110)

N° du produit ABIN562744

Cet anticorps Souris Monoclonal détecte spécifiquement RRM2 dans WB, ELISA, IF, IP et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 5+ publications.

Aperçu rapide pour RRM2 anticorps (AA 1-110) (ABIN562744)

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RRM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1E1

Détail du produit anti-RRM2 anticorps

Épitope: AA 1-110

Fonction: Mouse monoclonal antibody raised against a partial recombinant RRM2.

Séquence: MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: RRM2 (NP_001025, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RRM2 (ABIN562744)

Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." dans: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

Kim, Park, Joo, Shen, Hong, Kim, Singh, Lee, Shin: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." dans: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).

Yoshida, Tsunoda, Doi, Tanaka, Fujimoto, Machida, Ota, Koyanagi, Takashima, Sasazuki, Kuroki, Iwasaki, Shirasawa: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." dans: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).

Zhou, Snyder, Lieberman: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." dans: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).

Tang, Deng, Wang, Dai, Wang, Jiang, Li, Li, Sheng, Wu, Li, Zeng et al.: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." dans: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).

Détails sur RRM2

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Autre désignation: RRM2

Sujet: Full Gene Name: ribonucleotide reductase M2 polypeptide
Synonyms: R2,RR2M

ID gène: 6241

NCBI Accession: NM_001034

Pathways: Mitotic G1-G1/S Phases