CD41, CD61 anticorps (PAC-1 epitope)

N° du produit ABIN5633262

Cet anticorps Souris Monoclonal détecte spécifiquement CD41, CD61 dans FACS, IP et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour CD41, CD61 anticorps (PAC-1 epitope) (ABIN5633262)

Antigène: CD41, CD61 (CD41,CD61)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD41, CD61 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: PAC-1

Détail du produit anti-CD41, CD61 anticorps

Épitope: PAC-1 epitope

Fonction: Anti-Hu CD41/CD61 (PAC-1 epitope) Purified

Specificité: The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

Réactivité croisée (Details): Human

Purification: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human platelets

Isotype: IgM kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2-4 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur CD41, CD61

Antigène: CD41, CD61 (CD41,CD61)

Autre désignation: CD41/CD61

Sujet: CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa