AGR2 anticorps (AA 1-175)

N° du produit ABIN564604

Cet anticorps Souris Monoclonal détecte spécifiquement AGR2 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 9+ publications.

Aperçu rapide pour AGR2 anticorps (AA 1-175) (ABIN564604)

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AGR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1C3

Détail du produit anti-AGR2 anticorps

Épitope: AA 1-175

Fonction: Mouse monoclonal antibody raised against a full length recombinant AGR2.

Séquence: MEKIPVSAFL LLVALSYTLA RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: AGR2 (AAH15503.1, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-AGR2 (ABIN564604)

Dong, Wodziak, Lowe: "Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface." dans: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8016-27, (2015) (PubMed).

Riener, Thiesler, Hellerbrand, Amann, Cathomas, Fritzsche, Dahl, Bahra, Weichert, Terracciano, Kristiansen: "Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas." dans: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 10, pp. 1722-30, (2014) (PubMed).

Gray, Murray, Nowicki, Remnant, Scherl, Muller, Vojtesek, Hupp: "Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein." dans: Protein science : a publication of the Protein Society, Vol. 22, Issue 9, pp. 1266-78, (2013) (PubMed).

Wayner, Quek, Ahmad, Ho, Loprieno, Zhou, Ellis, True, Liu: "Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine." dans: The Prostate, Vol. 72, Issue 9, pp. 1023-34, (2012) (PubMed).

Darb-Esfahani, Fritzsche, Kristiansen, Weichert, Sehouli, Braicu, Dietel, Denkert: "Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma." dans: Virchows Archiv : an international journal of pathology, Vol. 461, Issue 2, pp. 109-16, (2012) (PubMed).

Lepreux, Bioulac-Sage, Chevet: "Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree." dans: Liver international : official journal of the International Association for the Study of the Liver, Vol. 31, Issue 3, pp. 322-8, (2011) (PubMed).

Ambolet-Camoit, Bui, Pierre, Chevallier, Marchand, Coumoul, Garlatti, Andreau, Barouki, Aggerbeck: "2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 2, pp. 501-12, (2010) (PubMed).

Maslon, Hrstka, Vojtesek, Hupp: "A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin." dans: Journal of molecular biology, Vol. 404, Issue 3, pp. 418-38, (2010) (PubMed).

Zhao, Lee, Brown, Molloy, Marx, Pavlakis, Boyer, Stockler, Kaplan, Breit, Sutherland, Henshall, Horvath: "Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling." dans: Cancer research, Vol. 69, Issue 19, pp. 7696-703, (2009) (PubMed).

Détails sur AGR2

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: AGR2

Sujet: Full Gene Name: anterior gradient homolog 2 (Xenopus laevis)
Synonyms: AG2,GOB-4,HAG-2,XAG-2

ID gène: 10551