Recombinant CD79a anticorps (AA 202-216)

N° du produit ABIN5646923

Cet anticorps anti-CD79a est un anticorps Lapin Monoclonal détectant CD79a dans FACS, IF et IHC (p). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Porc et Singe.

Aperçu rapide pour Recombinant CD79a anticorps (AA 202-216) (ABIN5646923)

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Singe

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD79a est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IGA-1790R

Détail du produit anti-CD79a anticorps

Épitope: AA 202-216

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD79a antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,IHC (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CD79a antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD79a

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: CD79a

Sujet: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

Pathways: BCR Signaling