LBP anticorps

N° du produit ABIN5647187

Cet anticorps anti-LBP est un anticorps Lapin Polyclonal détectant LBP dans WB et ELISA (Capture). Adapté pour Humain.

Aperçu rapide pour LBP anticorps (ABIN5647187)

Antigène: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LBP est non-conjugé

Application: Western Blotting (WB), ELISA (Capture)

Détail du produit anti-LBP anticorps

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids A26-R257 was used as the immunogen for the LBP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LBP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, recombinant human protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the LBP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur LBP

Antigène: LBP (Lipopolysaccharide Binding Protein (LBP))

Autre désignation: LBP / Lipopolysaccharide Binding Protein

Sujet: Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

UniProt: P18428

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process