Thrombopoietin anticorps

N° du produit ABIN5647289

Détail du produit anti-Thrombopoietin anticorps

Antigène: Thrombopoietin (THPO)

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombopoietin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: Amino acids S22-H259 from the mouse protein were used as the immunogen for the Thrombopoietin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Thrombopoietin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA: 0.1-0.5 μg/mL (mouse protein tested, request BSA-free format for coating)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Thrombopoietin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Thrombopoietin

Antigène: Thrombopoietin (THPO)

Autre désignation: Thrombopoietin / THPO (THPO Produits)

Synonymes: anticorps MGDF, anticorps MKCSF, anticorps ML, anticorps MPLLG, anticorps THCYT1, anticorps TPO, anticorps Mgdf, anticorps Ml, anticorps Mpllg, anticorps Tpo, anticorps Tpo1, anticorps Tpo2, anticorps Tpo3, anticorps Tpo4, anticorps tpo, anticorps LOC100231762, anticorps thrombopoietin, anticorps THPO, anticorps Thpo, anticorps thpo

Sujet: Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

UniProt: P40226

Pathways: Signalistation JAK/STAT, Hormone Activity