HTRA3 anticorps (AA 330-362)
Aperçu rapide pour HTRA3 anticorps (AA 330-362) (ABIN5647345)
Antigène
Voir toutes HTRA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 330-362
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Fonction
- HtrA3 Antibody
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Séquence
- FAIPSDRITR FLTEFQDKQI KDWKKRFIGI RMR
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Purification
- Antigen affinity
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Immunogène
- Amino acids 330-362 (FAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMR) from the human protein were used as the immunogen for the HtrA3 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the HtrA3 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the HtrA3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HTRA3 (HtrA Serine Peptidase 3 (HTRA3))
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Autre désignation
- HtrA3
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Sujet
- Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440)-binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.
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UniProt
- P83110
Antigène
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