HTRA3 anticorps (AA 334-453)
Aperçu rapide pour HTRA3 anticorps (AA 334-453) (ABIN7267790)
Antigène
Voir toutes HTRA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 334-453
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Fonction
- HTRA3 Rabbit pAb
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Séquence
- SDRITRFLTE FQDKQIKDWK KRFIGIRMRT ITPSLVDELK ASNPDFPEVS SGIYVQEVAP NSPSQRGGIQ DGDIIVKVNG RPLVDSSELQ EAVLTESPLL LEVRRGNDDL LFSIAPEVVM
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 334-453 of human HTRA3 (NP_444272.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- HTRA3 (HtrA Serine Peptidase 3 (HTRA3))
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Autre désignation
- HTRA3
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Sujet
- Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.,HTRA3,Prsp,Tasp,Signal Transduction,Neuroscience,Calcium Signaling,HTRA3
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Poids moléculaire
- 37kDa/48kDa
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ID gène
- 94031
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UniProt
- P83110
Antigène
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