AANAT anticorps (AA 27-54)
Aperçu rapide pour AANAT anticorps (AA 27-54) (ABIN5647916)
Antigène
Voir toutes AANAT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 27-54
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Western blot: 1:1000
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Restrictions
- For Research Use only
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the AANAT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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Autre désignation
- AANAT
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Sujet
- Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
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UniProt
- Q16613
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Pathways
- Photoperiodism
Antigène
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