ABHD5 anticorps (AA 1-349)

N° du produit ABIN565526

L’anticorps Souris Monoclonal anti-ABHD5 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter ABHD5 dans des échantillons de Humain. Il y a 11+ publications disponibles.

Aperçu rapide pour ABHD5 anticorps (AA 1-349) (ABIN565526)

Antigène: ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ABHD5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F3

Détail du produit anti-ABHD5 anticorps

Épitope: AA 1-349

Fonction: Mouse monoclonal antibody raised against a full length recombinant ABHD5.

Séquence: MAAEEEEVDS ADTGERSGWL TGWLPTWCPT SISHLKEAEE KMLKCVPCTY KKEPVRISNG NKIWTLKFSH NISNKTPLVL LHGFGGGLGL WALNFGDLCT NRPVYAFDLL GFGRSSRPRF DSDAEEVENQ FVESIEEWRC ALGLDKMILL GHNLGGFLAA AYSLKYPSRV NHLILVEPWG FPERPDLADQ DRPIPVWIRA LGAALTPFNP LAGLRIAGPF GLSLVQRLRP DFKRKYSSMF EDDTVTEYIY HCNVQTPSGE TAFKNMTIPY GWAKRPMLQR IGKMHPDIPV SVIFGARSCI DGNSGTSIQS LRPHSYVKTI AILGAGHYVY ADQPEEFNQK VKEICDTVD

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: ABHD5 (AAH21958, 1 a.a. ~ 349 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ABHD5 (ABIN565526)

Hofer, Boeszoermenyi, Jaeger, Feiler, Arthanari, Mayer, Zehender, Rechberger, Oberer, Zimmermann, Lass, Haemmerle, Breinbauer, Zechner, Preiss-Landl: "Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling." dans: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18438-53, (2015) (PubMed).

Kurtz, Peck, Fannin, Beysen, Miao, Landstreet, Ding, Turaga, Lund, Turner, Biddinger, Vickers, Sethupathy: "MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes." dans: Diabetes, Vol. 63, Issue 9, pp. 3141-8, (2014) (PubMed).

Patel, Yang, Kozusko, Saudek, Savage: "Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 25, pp. 9163-8, (2014) (PubMed).

Camus, Schweiger, Herker, Harris, Kondratowicz, Tsou, Farese, Herath, Previs, Roddy, Pinto, Zechner, Ott et al.: "The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid ..." dans: The Journal of biological chemistry, Vol. 289, Issue 52, pp. 35770-80, (2014) (PubMed).

Pollak, Schweiger, Jaeger, Kolb, Kumari, Schreiber, Kolleritsch, Markolin, Grabner, Heier, Zierler, Rülicke, Zimmermann, Lass, Zechner, Haemmerle: "Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier." dans: Journal of lipid research, Vol. 54, Issue 4, pp. 1092-102, (2013) (PubMed).

Guo, Ma, Kadegowda, Betters, Xie, Liu, Liu, Miao, Ou, Su, Zheng, Xue, Shi, Yu: "Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice." dans: Journal of lipid research, Vol. 54, Issue 8, pp. 2109-20, (2013) (PubMed).

Louche, Badin, Montastier, Laurens, Bourlier, de Glisezinski, Thalamas, Viguerie, Langin, Moro: "Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects." dans: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 12, pp. 4863-71, (2013) (PubMed).

Inoue, Kobayashi, Inoguchi, Sonoda, Maeda, Hirata, Fujimura, Miura, Hirano, Takayanagi: "Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice." dans: Biochemical and biophysical research communications, Vol. 438, Issue 1, pp. 224-9, (2013) (PubMed).

Grall, Guaguère, Planchais, Grond, Bourrat, Hausser, Hitte, Le Gallo, Derbois, Kim, Lagoutte, Degorce-Rubiales, Radner, Thomas, Küry, Bensignor, Fontaine, Pin, Zimmermann, Zechner, Lathrop, Galibert et al.: "PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. ..." dans: Nature genetics, Vol. 44, Issue 2, pp. 140-7, (2012) (PubMed).

Stenson, Rydén, Venteclef, Dahlman, Pettersson, Mairal, Aström, Blomqvist, Wang, Jocken, Clément, Langin, Arner, Laurencikiene: "Liver X receptor (LXR) regulates human adipocyte lipolysis." dans: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 370-9, (2011) (PubMed).

Kinney, Qiao, Levaugh, Shao: "B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice." dans: Endocrinology, Vol. 151, Issue 8, pp. 3624-32, (2010) (PubMed).

Détails sur ABHD5

Antigène: ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

Autre désignation: ABHD5

Sujet: Full Gene Name: abhydrolase domain containing 5
Synonyms: CDS,CGI58,IECN2,MGC8731,NCIE2

ID gène: 51099

Pathways: Lipid Metabolism