LBP anticorps

N° du produit ABIN5663309

Détail du produit anti-LBP anticorps

Antigène: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LBP est non-conjugé

Application: ELISA

Specificité: Human LBP (Lipopolysaccaride binding protein). The antibody don't block LPS binding to membrane bound CD14.

Réactivité croisée: Boeuf (Vache), Chien, Cheval, Lapin

Réactivité croisée (Details): pork, rabbit, dog, horse, bovine LBP

Purification: Protein G affinity column

Immunogène: native human LBP

Clone: BiG43

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with bidistilled water

Concentration: 1 mg/mL

Buffer: PBS, pH 7.13

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Détails sur LBP

Antigène: LBP (Lipopolysaccharide Binding Protein (LBP))

Autre désignation: LBP (LBP Produits)

Synonymes: anticorps BPIFD2, anticorps Bpifd2, anticorps Ly88, anticorps LPSBP, anticorps LBP, anticorps lipopolysaccharide binding protein, anticorps lipopolysaccharide-binding protein, anticorps LBP, anticorps Lbp, anticorps LOC100472839

Sujet: Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.

Poids moléculaire: ~58kDa

ID gène: 3929

NCBI Accession: NP_004130

UniProt: P18428

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process