POT1 anticorps (AA 497-634)

N° du produit ABIN5663924

L’anticorps Lapin Polyclonal anti-POT1 a été validé pour WB. Il convient pour détecter POT1 dans des échantillons de Humain.

Aperçu rapide pour POT1 anticorps (AA 497-634) (ABIN5663924)

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-POT1 anticorps

Épitope: AA 497-634

Séquence: TIHHYGCKQC SSLRSIQNLN SLVDKTSWIP SSVAEALGIV PLQYVFVMTF TLDDGTGVLE AYLMDSDKFF QIPASEVLMD DDLQKSVDMI MDMFCPPGIK IDAYPWLECF IKSYNVTNGT DNQICYQIFD TTVAEDVI

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur POT1

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Autre désignation: POT1

Sujet: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.,POT1,CMM10,GLM9,HPOT1,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,POT1

Poids moléculaire: 60 kDa/71 kDa

ID gène: 25913

UniProt: Q9NUX5

Pathways: Cycle Cellulaire, Telomere Maintenance