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Recombinant CD32/CD16 anticorps

Cet anticorps anti-CD32/CD16 est un anticorps Rat Monoclonal détectant CD32/CD16 dans FACS, IP, IF, BR et IHC. Adapté pour Souris.
N° du produit ABIN5668180

Aperçu rapide pour Recombinant CD32/CD16 anticorps (ABIN5668180)

Antigène

CD32/CD16

Type d'anticorp

Recombinant Antibody

Reactivité

Souris

Hôte

  • 51
  • 1
  • 1
Rat

Clonalité

  • 49
  • 1
  • 1
Monoclonal

Conjugué

  • 16
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD32/CD16 est non-conjugé

Application

  • 46
  • 7
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR), Immunohistochemistry (IHC)

Clone

2-4G2
  • Fonction

    Anti-CD16/CD32 [2.4G2], Rat IgG2b, kappa

    Specificité

    This antibody binds to an epitope on the extracellular domains of the mouse FcγIII and FcγII, thereby inhibiting their ability to bind antibodies via their Fc region. receptors. Also binding the FcγI receptor (CD64) via its Fc domain.

    Attributs du produit

    Original Species of Ab: Rat

    Original Format of Ab: IgG2b

    Purification

    Protein A affinity purified

    Immunogène

    Mouse BALB/c Macrophage J774 Cell Line.

    Isotype

    IgG2b kappa
  • Indications d'application

    This antibody binds murine Fc Receptors CD16/CD32 and inhibits binding of antibodies to these. It can therefore be used as an Fc-blocking reagent, to reduce non-specific staining of cells by antibodies binding via their Fc-region. A similar effect can be achieved using the Fc Silent range of antibodies made by Absolute Antibody that prevent these interactions at the level of the Fc receptor binding site, which has been mutated to lack affinity for the Fc receptors.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    CD32/CD16

    Autre désignation

    CD16/CD32

    Sujet

    Fcγ III/II Receptor, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII IgG Fc rec

    UniProt

    P08508, P08101
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