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Recombinant ITGA4 (Natalizumab Biosimilar) anticorps

L’anticorps Lapin Chimeric anti-ITGA4 (Natalizumab Biosimilar) a été validé pour FACS et BR. Il convient pour détecter ITGA4 (Natalizumab Biosimilar) dans des échantillons de Humain.
N° du produit ABIN5668197

Aperçu rapide pour Recombinant ITGA4 (Natalizumab Biosimilar) anticorps (ABIN5668197)

Antigène

ITGA4 (Natalizumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 3
  • 2
  • 1
  • 1
Lapin

Clonalité

  • 5
  • 2
Chimeric

Conjugué

  • 6
  • 1
Cet anticorp ITGA4 (Natalizumab Biosimilar) est non-conjugé

Application

Flow Cytometry (FACS), Blocking Reagent (BR)
  • Fonction

    Anti-Integrin alpha 4 [Natalizumab], Rabbit IgG, kappa

    Specificité

    This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin

    Attributs du produit

    Original Species of Ab: Human

    Original Format of Ab: IgG4

    Purification

    Protein A affinity purified

    Pureté

    > 98 % as determined by SDS-PAGE

    niveau d'endotoxine

    Endotoxin is < 1.0 EU/mg as determined by the LAL method

    Immunogène

    The RAMOS cell line, a non-EBV releasing cell line, injected into mice.

    Isotype

    IgG kappa
  • Indications d'application

    This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.

    Commentaires

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    ITGA4 (Natalizumab Biosimilar)

    Sujet

    CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV

    UniProt

    P13612
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