Recombinant CD55 anticorps

N° du produit ABIN5668199

Cet anticorps Lapin Chimeric détecte spécifiquement CD55 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CD55 anticorps (ABIN5668199)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: LU30

Détail du produit anti-CD55 anticorps

Fonction: Anti-CD55 [LU30], Rabbit IgG, lambda

Specificité: The antibody binds to CD55 with a Kd of 13 nM.

Attributs du produit: Human

Purification: Protein A affinity purified

Immunogène: Human CD55.

Isotype: IgG lambda

Information d'application

Indications d'application: The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55

Sujet: DAF, Complement decay-accelerating factor

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity