FKBP5 anticorps (N-Term)
Aperçu rapide pour FKBP5 anticorps (N-Term) (ABIN5671411)
Antigène
Voir toutes FKBP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- SNGKKFDSSH DRNEPFVFSL GKGQVIKAWD IGVATMKKGE ICHLLCKPEY
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP5
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FKBP5 (FK506 Binding Protein 5 (FKBP5))
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Autre désignation
- FKBP5
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Sujet
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Alias Symbols: P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10
Protein Size: 457 -
ID gène
- 2289
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NCBI Accession
- NM_001145775, NP_001139247
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UniProt
- Q13451
Antigène
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