SPG21 anticorps (N-Term)

N° du produit ABIN5671445

Cet anticorps Lapin Polyclonal détecte spécifiquement SPG21 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour SPG21 anticorps (N-Term) (ABIN5671445)

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG21 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPG21 anticorps

Épitope: N-Term

Séquence: GTVPLKKIIV DDDDSKIWSL YDAGPRSIRC PLIFLPPVSG TADVFFRQIL

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of Human SPG21

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPG21

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Autre désignation: SPG21

Sujet: The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: MAST, ACP33, GL010, BM-019

Protein Size: 281

ID gène: 51324

NCBI Accession: NM_001127889, NP_001121361