CDC14B anticorps (N-Term)
Aperçu rapide pour CDC14B anticorps (N-Term) (ABIN5672445)
Antigène
Voir toutes CDC14B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- KRKSERRSSW AAAPPCSRRC SSTSPGVKKI RSSTQQDPRR RDPQDDVYLD
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDC14B
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
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Autre désignation
- CDC14B
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Sujet
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The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Alias Symbols: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B
Protein Size: 498 -
ID gène
- 8555
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NCBI Accession
- NM_001077181, NP_001070649
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UniProt
- O60729
Antigène
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