SNAPIN anticorps (C-Term)

N° du produit ABIN5672645

Cet anticorps anti-SNAPIN Polyclonal Lapin (ABIN5672645) détecte spécifiquement SNAPIN dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SNAPIN anticorps (C-Term) (ABIN5672645)

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAPIN est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SNAPIN anticorps

Épitope: C-Term

Séquence: LLNARRRVVL VNNILQNAQE RLRRLNHSVA KETARRRAML DSGIYPPGSP

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SNAPIN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNAPIN

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Autre désignation: SNAPIN

Sujet: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: BLOS7, SNAPAP, BLOC1S7

Protein Size: 136

ID gène: 23557

NCBI Accession: NM_012437, NP_036569

UniProt: O95295

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis