Bystin-Like anticorps (C-Term)

N° du produit ABIN5672937

Cet anticorps Lapin Polyclonal détecte spécifiquement Bystin-Like dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Bystin-Like anticorps (C-Term) (ABIN5672937)

Antigène: Bystin-Like (BYSL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bystin-Like est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Bystin-Like anticorps

Épitope: C-Term

Séquence: LTLVQRYKAD LATDQKEALL ELLRLQPHPQ LSPEIRRELQ SAVPRDVEDV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human BYSL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Bystin-Like

Antigène: Bystin-Like (BYSL)

Autre désignation: BYSL

Sujet: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

Alias Symbols: BYSTIN

Protein Size: 437

ID gène: 705

NCBI Accession: NM_004053, NP_004044

UniProt: Q13895

Pathways: Cellular Response to Molecule of Bacterial Origin