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POLD1 anticorps
POLD1
Reactivité: Humain, Rat, Souris
WB
Hôte: Rat
Monoclonal
5G1
unconjugated
Détail du produit anti-POLD1 anticorps
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Antigène
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POLD1
(Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))
Reactivité
Toutes les réactivités sur POLD1 Anticorps
Humain, Rat, Souris
Hôte
Toutes les hôtes sur POLD1 Anticorps
Rat
Clonalité
Toutes les clonalités sur POLD1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers POLD1 Anticorps
Cet anticorp POLD1 est non-conjugé
Application
Tous les applications à travers POLD1 Anticorps.
Western Blotting (WB)
Specificité
This antibody reacts with DNA polymerase delta p125 catalytic subunit (125 kDa) by Western blotting.
Purification
Protein-G Agarose Chromatography of hybridoma supernatant.
Immunogène
Recombinant full length His-Human p125.
Clone
5G1
Isotype
IgG2a
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS, pH 7.2 containing 50 % Glycerol without preservatives.
Agent conservateur
Without preservative
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C.
Détails sur POLD1
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Antigène
POLD1
(Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))
Autre désignation
POLD1 (POLD1 Produits )
Synonymes
anticorps CDC2, anticorps CRCS10, anticorps POLD, anticorps 5949, anticorps CAA61369, anticorps CG5949, anticorps DNA Pol Delta, anticorps Dm Poldelta, anticorps Dmel\\CG5949, anticorps Poldelta, anticorps dnapol delta, anticorps l(3)72Ac, anticorps cdc2, anticorps pold, anticorps 125kDa, anticorps Pol delta, anticorps fla, anticorps im:7139126, anticorps zgc:152688, anticorps DNA polymerase delta 1, catalytic subunit, anticorps DNA-polymerase-delta, anticorps polymerase (DNA directed), delta 1, catalytic subunit, anticorps DNA polymerase delta catalytic subunit, anticorps DNA polymerase delta, anticorps POLD1, anticorps DNApol-delta, anticorps pold1, anticorps LOC100456571, anticorps Pold1
Sujet
In eukaryotic cells, 3 types of DNA polymerases (pol), pol alpha, pol delta and pol epsilon function in accurate and efficient DNA replication. Pol delta is a heteromultimeric enzyme composed of a 125 kDa major catalytic subunit and three smaller accessory subunits. Pol delta requires a number of accessory molecules to exert its full activity. Proliferating cell nuclear antigen (PCNA) forms a doughnut-shaped trimer with a 35 Ä hole and works as the sliding clamp and replication factor C acts as the clamp loader to improve Pol delta processivity. Pol delta is also involved in nucleotide excision repair of DNA.Synonyms: DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125
ID gène
5424
NCBI Accession
NP_002682
UniProt
P28340
Pathways
Telomere Maintenance , Réparation de l'ADN , DNA Replication , Chromatin Binding , Synthesis of DNA
Vus récemment
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