POLD1 anticorps

N° du produit ABIN567776

Détail du produit anti-POLD1 anticorps

Antigène: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Reactivité: Humain, Rat, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp POLD1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts with DNA polymerase delta p125 catalytic subunit (125 kDa) by Western blotting.

Purification: Protein-G Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant full length His-Human p125.

Clone: 5G1

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur POLD1

Antigène: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Autre désignation: POLD1 (POLD1 Produits)

Synonymes: anticorps CDC2, anticorps CRCS10, anticorps POLD, anticorps 5949, anticorps CAA61369, anticorps CG5949, anticorps DNA Pol Delta, anticorps Dm Poldelta, anticorps Dmel\\CG5949, anticorps Poldelta, anticorps dnapol delta, anticorps l(3)72Ac, anticorps cdc2, anticorps pold, anticorps 125kDa, anticorps Pol delta, anticorps fla, anticorps im:7139126, anticorps zgc:152688, anticorps DNA polymerase delta 1, catalytic subunit, anticorps DNA-polymerase-delta, anticorps polymerase (DNA directed), delta 1, catalytic subunit, anticorps DNA polymerase delta catalytic subunit, anticorps DNA polymerase delta, anticorps POLD1, anticorps DNApol-delta, anticorps pold1, anticorps LOC100456571, anticorps Pold1

Sujet: In eukaryotic cells, 3 types of DNA polymerases (pol), pol alpha, pol delta and pol epsilon function in accurate and efficient DNA replication. Pol delta is a heteromultimeric enzyme composed of a 125 kDa major catalytic subunit and three smaller accessory subunits. Pol delta requires a number of accessory molecules to exert its full activity. Proliferating cell nuclear antigen (PCNA) forms a doughnut-shaped trimer with a 35 Ä hole and works as the sliding clamp and replication factor C acts as the clamp loader to improve Pol delta processivity. Pol delta is also involved in nucleotide excision repair of DNA.Synonyms: DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125

ID gène: 5424

NCBI Accession: NP_002682

UniProt: P28340

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Chromatin Binding, Synthesis of DNA