TXNIP anticorps

N° du produit ABIN567793

Cet anticorps Souris Monoclonal détecte spécifiquement TXNIP dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TXNIP anticorps (ABIN567793)

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TXNIP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: JY1

Détail du produit anti-TXNIP anticorps

Specificité: This antibody reacts with VDUP-1 (50 kDa) by Western blotting.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Human recombinant VDUP-1/Txnip.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur TXNIP

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Autre désignation: TXNIP / VDUP1

Sujet: Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1

ID gène: 10628

NCBI Accession: NP_006463

UniProt: Q9H3M7

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome