TXNIP anticorps

N° du produit ABIN567794

L’anticorps Souris Monoclonal anti-TXNIP a été validé pour WB, IP et IHC (p). Il convient pour détecter TXNIP dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TXNIP anticorps (ABIN567794)

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TXNIP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: JY2

Détail du produit anti-TXNIP anticorps

Specificité: This antibody reacts with Txnip/VDUP1 (50 kDa) on Western blotting and Immunoprecipitation.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Human recombinant VDUP-1/Txnip.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur TXNIP

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Autre désignation: TXNIP / VDUP1

Sujet: Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that Txnip plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1

ID gène: 10628

NCBI Accession: NP_006463

UniProt: Q9H3M7

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome