GUK1 anticorps (Biotin)

N° du produit ABIN568250

L’anticorps Lapin Polyclonal anti-GUK1 a été validé pour WB, IP, IF, DB, EIA, ID et RIA. Il convient pour détecter GUK1 dans des échantillons de Porc.

Aperçu rapide pour GUK1 anticorps (Biotin) (ABIN568250)

Antigène: GUK1 (Guanylate Kinase 1 (GUK1))

Reactivité: Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GUK1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Dot Blot (DB), Enzyme Immunoassay (EIA), Immunodiffusion (ID), Radioimmunoassay (RIA)

Détail du produit anti-GUK1 anticorps (Biotin)

Attributs du produit: Molar Ratio: Biotin/IgG = ~6.6

Purification: Ammonium Sulphate Precipitation and Ion Exchange Chromatography.

Immunogène: Guanylate kinase isolated and purified from Porcine brain. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore by adding 1.0 mL sterile distilled water.

Concentration: 10.0 mg/mL

Buffer: PBS, pH 7.2 without preservatives and foreign proteins.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.

Détails sur GUK1

Antigène: GUK1 (Guanylate Kinase 1 (GUK1))

Autre désignation: Guanylate Kinase / GUK1

Sujet: Guanylate kinase catalyzes the transfer of phosphate from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) or dGMP. This enzyme functions in the recovery of cGMP and is, therefore, thought to regulate the supply of guanine nucleotides to signal transduction pathways. The GUK2 and GUK3 isoforms are determined by separate loci. Brady et al. (1996) cloned human and mouse cDNAs of GUK1. They stated that the guanylate kinases are targets for cancer chemotherapy and are inhibited by the antitumor drug 6-thioguanine. They reported that the human gene codes for a protein of 197 amino acids with a mass of 21.7 kD. They found that the 1-kb message was ubiquitously expressed.Synonyms: GMK, GMP kinase

ID gène: 9823

UniProt: P31006

Pathways: Nucleotide Phosphorylation, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process