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Isocitrate Dehydrogenase anticorps (Biotin)

IDH Reactivité: Porc WB, IF, IP, EIA, DB, ID, RIA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN568271
  • Antigène Voir toutes Isocitrate Dehydrogenase (IDH) Anticorps
    Isocitrate Dehydrogenase (IDH)
    Reactivité
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Porc
    Hôte
    • 12
    • 1
    Lapin
    Clonalité
    • 13
    Polyclonal
    Conjugué
    • 9
    • 3
    • 1
    Cet anticorp Isocitrate Dehydrogenase est conjugé à/à la Biotin
    Application
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Dot Blot (DB), Immunodiffusion (ID), Radioimmunoassay (RIA)
    Attributs du produit
    Molar Ratio: Biotin/IgG ~6.5
    Purification
    Ammonium Sulphate Precipitation and Ion Exchange Chromatography
    Immunogène
    Isocitrate Dehydrogenase isolated and purified from Porcine heart. Freund’s complete adjuvant is used in the first step of the immunization procedure.
    Isotype
    IgG
    Top Product
    Discover our top product IDH Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    Restore by adding 1.0 mL sterile distilled water
    Concentration
    10 mg/mL
    Buffer
    PBS, pH 7.2 without preservatives and foreign proteins
    Agent conservateur
    Without preservative
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
  • Antigène
    Isocitrate Dehydrogenase (IDH)
    Autre désignation
    Isocitrate Dehydrogenase / IDH (IDH Produits)
    Synonymes
    anticorps CG7176, anticorps CT22171, anticorps Dmel\\CG7176, anticorps IDH, anticorps IDH-NADP, anticorps Idh-NADP, anticorps idh, anticorps isocitrate dehydrogenase, anticorps l(3)L3852, anticorps F20D21.16, anticorps F20D21_16, anticorps SMU.672, anticorps icd, anticorps Isocitrate dehydrogenase, anticorps isocitrate dehydrogenase, anticorps isocitrate dehydrogenase, NADP-dependent, anticorps Monomeric isocitrate dehydrogenase, anticorps ankyrin repeat domain 26-like, anticorps Idh, anticorps ICDH, anticorps idh, anticorps icd, anticorps SSO_RS10660, anticorps JK_RS08640, anticorps LOC618625
    Sujet
    Isocitrate dehydrogenase is an enzyme involved in the citric acid cycle. It is 416 amino acids long with a molecular weight of approximately 45 kDa. Isocitrate dehydrogenase enzymes catalyze the oxidative decarboxylation of isocitrate to produce alfa ketoglutarate. The human genome has 5 IDH genes coding for 3 IDH enzymes. The IDH1 and IDH2 require nicotinamide adeninedinucleotide phosphate (NADP) as co-substrate, whereas IDH3 require nicotinamide adenine dinucleotide (NAD). The IDH2 and 3 are localized in mitochondria and are actively involved in the citric acid cycle (TCA) for energy production in contrast, IDH1 is localized in cytoplasm and peroxisomes where it generates NADPH, reduced form of NADP for biosynthetic and other types of reaction. Since alfa KG and NADPH both are intermediately substrate for a number of cellular process, which allows the possibility of oncogenic or tumor suppressive activities of IDH1.Synonyms: Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD, cytoplasmic Isocitrate dehydrogenase [NADP]
    ID gène
    9823
    UniProt
    P20304
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