PLA2G1B anticorps

N° du produit ABIN568377

Cet anticorps anti-PLA2G1B est un anticorps Lapin Polyclonal détectant PLA2G1B dans WB, IF, ID, IP, DB, EIA et RIA. Adapté pour Bee.

Aperçu rapide pour PLA2G1B anticorps (ABIN568377)

Antigène: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Reactivité: Bee

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G1B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunodiffusion (ID), Immunoprecipitation (IP), Dot Blot (DB), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Détail du produit anti-PLA2G1B anticorps

Specificité: Phospholipase A2 from bee venom. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, Single Radial Immunodiffusion (Ouchterlony), Block Titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.

Purification: Ammonium Sulphate Precipitation and Ion Exchange Chromatography.

Immunogène: Phospholipase A2 isolated and purified from bee venom. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore by adding 1 mL of sterile distilled water.

Concentration: 10 mg/mL

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid Repeated thawing and freezing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer.

Détails sur PLA2G1B

Antigène: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Autre désignation: Phospholipase A2

Sujet: Phospholipase A2 catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid, a precursor of eicosanoids including prostaglandins and leukotrienes. This enzyme has been proposed to hydrolyze phosphatidylcholine in lipoproteins to liberate lyso-PC and free fatty acids in the arterial wall, thereby facilitating the accumulation of bioactive lipids and modified lipoproteins in atherosclerotic foci. Phospholipase A2 IIA can exert beneficial action in the context of infectious diseases since recent studies have shown that this enzyme exhibits potent bactericidal effects. Induction of the synthesis of Phospholipase A2 IIA is generally initiated by endotoxin and a limited number of cytokines via paracrine and/or autocrine processes.Synonyms: Allergen Api m I, Phosphatidylcholine 2-acylhydrolase

ID gène: 406141

NCBI Accession: NP_001011614

UniProt: P00630

Pathways: Inositol Metabolic Process, VEGF Signaling