POR anticorps (Internal Region)
Aperçu rapide pour POR anticorps (Internal Region) (ABIN568710)
Antigène
Voir toutes POR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Séquence
- C-TNPPRTNVLY E
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Specificité
- Recognizes Cytochrome P450 Reductase (CYPOR).
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Réactivité croisée (Details)
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Species reactivity (expected):Dog, Cow, Pig, Rabbit.
Species reactivity (tested):Human, Mouse, Rat. -
Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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Immunogène
- Peptide with sequence from the internal region of the protein sequence according to NP_000932.3. Genename: POR
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- POR (P450 (Cytochrome) Oxidoreductase (POR))
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Autre désignation
- Cytochrome P450 Reductase
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Sujet
- P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.Synonyms: CPR, CYPOR, NADPH--cytochrome P450 reductase, P450R, POR
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ID gène
- 5447
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NCBI Accession
- NP_000932
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UniProt
- P16435
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
Antigène
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