TUBB3 anticorps

N° du produit ABIN5688672

Cet anticorps Souris Monoclonal détecte spécifiquement TUBB3 dans WB et IHC. Il présente une réactivité envers Mammifères.

Aperçu rapide pour TUBB3 anticorps (ABIN5688672)

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Mammifères

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AA10

Détail du produit anti-TUBB3 anticorps

Specificité: Specific for the ~55  kDa beta III tubulin protein. This clone is similar to the monoclonal antibody Tuj1.

Purification: Protein G purified

Immunogène: Synthetic peptide corresponding to beta III tubulin.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Beta III Tubulin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: Beta III Tubulin

Sujet: Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)

Poids moléculaire: 55 kDa

ID gène: 246118

UniProt: Q4QRB4

Pathways: Dynamique des Microtubules, M Phase