Potassium Channel (pSer503) anticorps

N° du produit ABIN5688902

Cet anticorps anti-Potassium Channel Polyclonal Lapin (ABIN5688902) détecte spécifiquement Potassium Channel dans WB et IHC. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour Potassium Channel (pSer503) anticorps (ABIN5688902)

Antigène: Potassium Channel

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Épitope: pSer503

Purification: Affinity Purified

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH).

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots with rat and mouse tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Potassium Channel antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détail du antigène

Antigène: Potassium Channel

Sujet: Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995, Pongs, 1999, Blaine and Ribera, 1998, Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).

Poids moléculaire: 100 kDa

ID gène: 25327

UniProt: P25122