Cet anticorps Lapin Polyclonal détecte spécifiquement Potassium Channel dans WB et IHC. Il présente une réactivité avec des échantillons de Rat et Xenopus laevis.
Reactivité: Rat, Souris
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Potassium Channel antibody can be used for specific immunolabeling of the ~125k Kv 2.2 protein in Western blots. Applications include Dot Blots (DB), Immunohistochemistry (IHC) and Western Blots (WB). Rabbit anti-Potassium Channel, Kv2.2 recognizes Kv2.2 in rat and Xenopus. When internally tested under ideal conditions the working dilutions were 1:1000 for IHC, DB and WB.
Restrictions
For Research Use only
Format
Liquid
Buffer
100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
Stock
-20 °C
Stockage commentaire
Potassium Channel, Kv2.2 Subunit antibody can be stored at -20°C. After reconstitution in 50 μ,l PBS, the antibody should be aliquot and stored at -20°C and is stable at -20°C for at least 1 year. Ambient shipment is suitable for both international and domestic.
Antigène
Potassium Channel
Sujet
Voltage-gated K+ channels are important determinants of neuronal membrane excitability, and differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes. Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells.