SYN1 anticorps (pSer549)

N° du produit ABIN5688905

Cet anticorps anti-SYN1 est un anticorps Lapin Polyclonal détectant SYN1 dans WB et IHC. Adapté pour Humain, Rat, Souris, Boeuf (Vache) et Chien.

Aperçu rapide pour SYN1 anticorps (pSer549) (ABIN5688905)

Antigène: SYN1 (Synapsin I (SYN1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SYN1 anticorps

Épitope: pSer549

Purification: Affinity Purified

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser549 of synapsin I.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, non-human primate, bovine and canine tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Synapsin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur SYN1

Antigène: SYN1 (Synapsin I (SYN1))

Autre désignation: Synapsin

Sujet: Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.

Poids moléculaire: 78 kDa

ID gène: 281510

UniProt: P17599