Synaptotagmin anticorps (Ser309)
Aperçu rapide pour Synaptotagmin anticorps (Ser309) (ABIN5688918)
Antigène
Voir toutes Synaptotagmin (SYT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Ser309
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Specificité
- Synaptotagmin antibody is specific for Mr 60 - 62k synaptotagmin phosphorylated at Ser309.
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Purification
- Affinity Purified
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Immunogène
- Synaptotagmin (Ser309) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser309 of synaptotagmin.
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Indications d'application
- Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not yet been determined. Human, mouse, and rat have 100 % amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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Stock
- -20 °C
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Stockage commentaire
- For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
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- Synaptotagmin (SYT)
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Autre désignation
- Synaptotagmin
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Sujet
- Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis. Moreover recent studies indicate that the protein also plays a key role in endocytosis. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission.
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Poids moléculaire
- 60/62 kDa
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ID gène
- 25716
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UniProt
- P21707
Antigène
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