SYN1 anticorps (pSer609)

N° du produit ABIN5688923

Cet anticorps anti-SYN1 est un anticorps Lapin Polyclonal détectant SYN1 dans WB. Adapté pour Rat.

Aperçu rapide pour SYN1 anticorps (pSer609) (ABIN5688923)

Antigène: SYN1 (Synapsin I (SYN1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SYN1 anticorps

Épitope: pSer609

Specificité: Synapsin antibody is specific for Synapsin I phosphorylated at Ser603.

Purification: Affinity Purified

Immunogène: Synapsin (Ser603) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phosphorylated Ser609 of Rat Synapsin I.

Information d'application

Indications d'application: Immunolabeling of the 78k Synapsin I doublet in a Western blot of rat brain homogenate is blocked by the phosphopeptide used as antigen but not by the corresponding non-phosphopeptide. Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not yet been determined. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

Détails sur SYN1

Antigène: SYN1 (Synapsin I (SYN1))

Autre désignation: Synapsin

Sujet: Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function.

Poids moléculaire: 78 kDa

ID gène: 281510

UniProt: P17599