AIMP1 anticorps (AA 240-290)

N° du produit ABIN5688956

Cet anticorps anti-AIMP1 Polyclonal Lapin (ABIN5688956) détecte spécifiquement AIMP1 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AIMP1 anticorps (AA 240-290) (ABIN5688956)

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-AIMP1 anticorps

Épitope: AA 240-290

Specificité: AIMP1 antibody is human, mouse and rat reactive. At least two isoforms of AIMP1 are known to exist, this antibody will recognize both isoforms. AIMP1 antibody is predicted to not cross-react with AIMP2.

Purification: AIMP1 antibody is affinity chromatography purified via peptide column.

Immunogène: AIMP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AIMP1.

The immunogen is located within amino acids 240 - 290 of AIMP1.

Isotype: IgG

Information d'application

Indications d'application: AIMP1 antibody can be used for detection of AIMP1 by Western blot at 1 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AIMP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: AIMP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur AIMP1

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Autre désignation: AIMP1

Sujet: AIMP1 (Endothelial monocyte-activating polypeptide II, EMAP2) is a proinflammatory cytokine for monocytes and granulocytes (1). It is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing (1,2). AIMP1 was identified as one of three auxiliary factors of the mammalian aminoacyl tRNA synthetase (ARS) complex. It binds and facilitates the catalytic reaction of arginyl-tRNA synthetase (2,3). Recent studies show that CD23 plays an essential role in the AIMP1-induced immune response and might be a target in the treatment of inflammatory diseases (4).

Poids moléculaire: Predicted: 46 kDa

Observed: 36 kDa

ID gène: 9255

NCBI Accession: NP_001135888

UniProt: Q12904