CDC25B anticorps (pSer149)

N° du produit ABIN5689217

Cet anticorps anti-CDC25B est un anticorps Lapin Polyclonal détectant CDC25B dans WB. Adapté pour Souris et Rat.

Aperçu rapide pour CDC25B anticorps (pSer149) (ABIN5689217)

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC25B anticorps

Épitope: pSer149

Specificité: This antibody detects endogenous level of Cdc25B protein only when phosphorylated at serine 149.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Cdc25B (Phospho-Ser149) antibody was raised against a peptide sequence around phosphorylation site of Serine 149 (F-R-S (p) -L-P) derived from Mouse Cdc25B.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur CDC25B

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Autre désignation: Cdc25B

Sujet: Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.

Poids moléculaire: 62 kDa

ID gène: 12531

NCBI Accession: NP_001104545

UniProt: Q9DBN8

Pathways: Cycle Cellulaire, M Phase, Autophagy