Integrin beta 3 anticorps (AA 783-787)

N° du produit ABIN5689254

Cet anticorps Lapin Polyclonal détecte spécifiquement Integrin beta 3 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Integrin beta 3 anticorps (AA 783-787) (ABIN5689254)

Antigène: Integrin beta 3 (ITGB3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Integrin beta 3 anticorps

Épitope: AA 783-787

Specificité: This antibody detects endogenous level of total Integrin β,3 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Integrin beta3 (Ab-785) antibody was raised against a peptide sequence around aa.783~787 (I-T-Y-R-G) derived from Human Integrin B3/ITGB3.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur Integrin beta 3

Antigène: Integrin beta 3 (ITGB3)

Autre désignation: Integrin beta3

Sujet: The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with Alpha and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct Alpha subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-Alpha2B or the Itg-Beta3 subunit

Poids moléculaire: 110 kDa

ID gène: 3690

NCBI Accession: NP_000203

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex