BCL2L1 anticorps (AA 60-64)

N° du produit ABIN5689429

L’anticorps Lapin Polyclonal anti-BCL2L1 a été validé pour WB. Il convient pour détecter BCL2L1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCL2L1 anticorps (AA 60-64) (ABIN5689429)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BCL2L1 anticorps

Épitope: AA 60-64

Specificité: This antibody detects endogenous level of total BCL-XL protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: BCL-XL (Ab-62) antibody was raised against a peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL .

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: BCL XL

Sujet: Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.

Poids moléculaire: 30 kDa

ID gène: 598

NCBI Accession: NP_612815

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling