BIM anticorps (AA 67-71)

N° du produit ABIN5689506

Cet anticorps Lapin Polyclonal détecte spécifiquement BIM dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour BIM anticorps (AA 67-71) (ABIN5689506)

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-BIM anticorps

Épitope: AA 67-71

Specificité: This antibody detects endogenous level of total BIM protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: BIM (Ab-69) antibody was raised against a peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur BIM

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Autre désignation: BIM

Sujet: Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.

Poids moléculaire: 23 kDa

ID gène: 10018

NCBI Accession: NP_006529

UniProt: O43521

Pathways: Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity