MBP anticorps (AA 291-295)

N° du produit ABIN5689532

Cet anticorps anti-MBP est un anticorps Lapin Polyclonal détectant MBP dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MBP anticorps (AA 291-295) (ABIN5689532)

Antigène: MBP (Myelin Basic Protein (MBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MBP anticorps

Épitope: AA 291-295

Specificité: This antibody detects endogenous level of total MBP(myelin basic protein) protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: MBP (myelin basic protein) antibody was raised against a peptide sequence around aa.291~295 (G-G-R-D-S) derived from Human MBP.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur MBP

Antigène: MBP (Myelin Basic Protein (MBP))

Autre désignation: Myelin basic protein

Sujet: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Poids moléculaire: 14~33 kDa

ID gène: 4155

NCBI Accession: NP_001020252

UniProt: P02686