REST anticorps (AA 873-877)

N° du produit ABIN5689634

Cet anticorps anti-REST est un anticorps Lapin Polyclonal détectant REST dans WB. Adapté pour Humain.

Aperçu rapide pour REST anticorps (AA 873-877) (ABIN5689634)

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REST est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-REST anticorps

Épitope: AA 873-877

Specificité: This antibody detects endogenous level of total REST protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: REST antibody was raised against a peptide sequence around aa.873~877 (R-E-E-A-S) derived from Human REST.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur REST

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Autre désignation: REST

Sujet: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Poids moléculaire: 121 kDa

ID gène: 5978

NCBI Accession: NP_001180437

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity