APOE anticorps (AA 220-270)

N° du produit ABIN5689876

L’anticorps Lapin Polyclonal anti-APOE a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter APOE dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour APOE anticorps (AA 220-270) (ABIN5689876)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-APOE anticorps

Épitope: AA 220-270

Purification: APO-E Antibody is affinity chromatography purified via peptide column.

Immunogène: APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E.

The immunogen is located within amino acids 220 - 270 of APO-E.

Isotype: IgG

Information d'application

Indications d'application: APO-E antibody can be used for detection of APO-E by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: APO-E Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: APO-E antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: APO-E

Sujet: APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Poids moléculaire: Predicted: 35 kDa

Observed: 34 kDa

ID gène: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism