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SKIV2L anticorps (AA 260-310)

L’anticorps Lapin Polyclonal anti-SKIV2L a été validé pour ELISA, WB, IF et IHC (p). Il convient pour détecter SKIV2L dans des échantillons de Humain et Souris.
N° du produit ABIN5689978

Aperçu rapide pour SKIV2L anticorps (AA 260-310) (ABIN5689978)

Antigène

Voir toutes SKIV2L Anticorps
SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Reactivité

  • 8
  • 2
  • 1
  • 1
Humain, Souris

Hôte

  • 5
  • 3
Lapin

Clonalité

  • 7
  • 1
Polyclonal

Conjugué

  • 8
Cet anticorp SKIV2L est non-conjugé

Application

  • 7
  • 5
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-310

    Specificité

    GPRASP1 antibody is human and mouse reactive. This antibody is predicted to not cross-react with GPRASP2.

    Purification

    GPRASP1 antibody is affinity chromatography purified via peptide column.

    Immunogène

    GPRASP1 antibody was raised against a 15 amino acid peptide near the amino terminus of human GPRASP1.

    The immunogen is located within amino acids 260 - 310 of GPRASP1.

    Isotype

    IgG
  • Indications d'application

    GPRASP1 antibody can be used for detection of GPRASP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    GPRASP1 antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    GPRASP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Antigène

    SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

    Autre désignation

    SKI2W

    Sujet

    The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2). GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2). Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3).

    Poids moléculaire

    Predicted: 153 kDa

    Observed: 150 kDa

    ID gène

    9737

    NCBI Accession

    NP_001171656

    UniProt

    Q5JY77
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