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KREMEN2 anticorps (AA 390-440)
KREMEN2
Reactivité: Humain, Souris
WB, ELISA, ICC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5690035
Détail du produit anti-KREMEN2 anticorps
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Antigène
Voir toutes KREMEN2 Anticorps
KREMEN2
(Kringle Containing Transmembrane Protein 2 (KREMEN2))
Épitope
Tous les épitopes à travers KREMEN2 Anticorps.
AA 390-440
Reactivité
Toutes les réactivités sur KREMEN2 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur KREMEN2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur KREMEN2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers KREMEN2 Anticorps
Cet anticorp KREMEN2 est non-conjugé
Application
Tous les applications à travers KREMEN2 Anticorps.
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
Specificité
Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
Purification
KREMEN2 Antibody is affinity chromatography purified via peptide column.
Immunogène
KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2 . The immunogen is located within amino acids 390 - 440 of KREMEN2.
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
KREMEN2 Antibody can be used for detection of KREMEN2 by Western blot starting at 1 μ,g/mL.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
KREMEN2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
KREMEN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Détails sur KREMEN2
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Antigène
KREMEN2
(Kringle Containing Transmembrane Protein 2 (KREMEN2))
Autre désignation
KREMEN2 (KREMEN2 Produits )
Synonymes
anticorps krm2, anticorps KREMEN2, anticorps MGC147633, anticorps KRM2, anticorps 2900054E04Rik, anticorps Krm2, anticorps kringle containing transmembrane protein 2 S homeolog, anticorps kringle containing transmembrane protein 2, anticorps kremen2.S, anticorps KREMEN2, anticorps kremen2, anticorps Kremen2
Sujet
KREMEN2 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) co-receptor. Recent experiments have shown that KREMEN2 is a regulator of bone remodeling and raise the possibility that antagonizing KREMEN2 might prove beneficial in patients with bone loss disorders.
Poids moléculaire
Predicted: 51 kDa Observed: 54 kDa
ID gène
79412
NCBI Accession
NP_757384
UniProt
Q8NCW0
Pathways
Signalisation WNT
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