NADPH Oxidase 4 anticorps (AA 70-120)
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- Antigène Voir toutes NADPH Oxidase 4 (NOX4) Anticorps
- NADPH Oxidase 4 (NOX4)
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Épitope
- AA 70-120
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NADPH Oxidase 4 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- NOX4 antibody is human, mouse, and rat reactive. At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins.
- Purification
- NOX4 antibody is affinity chromatography purified via peptide column.
- Immunogène
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NOX4 antibody was raised against a 14 amino acid peptide near the amino terminus of human NOX4.
The immunogen is located within amino acids 70 - 120 of NOX4. - Isotype
- IgG
- Top Product
- Discover our top product NOX4 Anticorps primaire
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- Indications d'application
- NOX4 antibody can be used for detection of NOX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- NOX4 antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- NOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- NADPH Oxidase 4 (NOX4)
- Autre désignation
- NOX4 (NOX4 Produits)
- Synonymes
- anticorps KOX, anticorps KOX-1, anticorps RENOX, anticorps AI648021, anticorps nox4, anticorps NOX4, anticorps NADPH oxidase 4, anticorps NOX4, anticorps Nox4, anticorps nox4, anticorps PTRG_09562
- Sujet
- The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX4 is is expressed in multiple tissues and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) (2,3). Unlike other NOX proteins, NOX4 does not require cytosolic subunits and thus is constitutively active (4). The function of NOX4 remains unclear as it plays both protective and deleterious roles in cellular metabolism.
- Poids moléculaire
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Predicted: 64 kDa
Observed: 68 kDa - ID gène
- 50507
- NCBI Accession
- NP_058627
- UniProt
- Q9NPH5
- Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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