SPIB anticorps (AA 200-250)

N° du produit ABIN5690267

Détail du produit anti-SPIB anticorps

Antigène: SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Épitope: AA 200-250

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPIB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: SPIB antibody is human, mouse and rat reactive. At least four isoforms of SPIB are known to exist, this antibody will detect all but isoform 3.

Purification: SPIB antibody is affinity chromatography purified via peptide column.

Immunogène: SPIB antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SPIB.

The immunogen is located within amino acids 200 - 250 of SPIB.

Isotype: IgG

Information d'application

Indications d'application: SPIB antibody can be used for detection of SPIB by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SPIB antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SPIB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SPIB

Antigène: SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Autre désignation: SPIB (SPIB Produits)

Synonymes: anticorps spi-b, anticorps spib, anticorps spiba, anticorps SPI-B, anticorps B42b-like, anticorps Spi-B, anticorps Spi-B transcription factor L homeolog, anticorps Spi-B transcription factor, anticorps Spi-B transcription factor (Spi-1/PU.1 related), anticorps spib.L, anticorps SPIB, anticorps Spib

Sujet: SPIB is a member of the ETS transcription factor family that influences lymphoid development and activity and binds the consensus DNA site GGA (A/T) through a unique winged helix-turn-helix motif known as the ETS domain (1). SPIB is found in hematopoietic cells such as B cells and plasmacytoid dendritic cells (DC) (2,3). It promotes the development of plasmacytoid dendritic cells (pDCs) or natural interferon (IFN)-producing cells. SPIB may be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation (3,4).

Poids moléculaire: Predicted: 19, 25, 29 kDa

Observed: 20 kDa

ID gène: 6689

NCBI Accession: NP_003112

UniProt: Q01892