C7 anticorps (AA 233-453)

N° du produit ABIN5692807

L’anticorps Lapin Polyclonal anti-C7 a été validé pour WB et ELISA. Il convient pour détecter C7 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour C7 anticorps (AA 233-453) (ABIN5692807)

Antigène: C7 (Complement Component C7 (C7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-C7 anticorps

Épitope: AA 233-453

Fonction: Anti-Complement C7 Antibody Picoband®

Marque: Picoband™

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Complement C7 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Complement C7 recombinant protein (Position: R233-D453).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Barroso, S., Rieubland, C., Alvarez, A. J., Lopez-Trascasa, M., Bart, P.-A., Nunez-Roldan, A., Sanchez, B. Molecular defects of the C7 gene in two patients with complement C7deficiency. Immunology 118: 257-260, 2006. 2. Coto, E., Martinez-Naves, E., Dominguez, O., DiScipio, R. G., Urra, J. M., Lopez-Larrea, C.DNA polymorphism and linkage relationship of the human complement component C6,C7, and C9 genes. Immunogenetics 33: 184-187, 1991.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur C7

Antigène: C7 (Complement Component C7 (C7))

Autre désignation: C7

Sujet:

Synonyms: Complement component C7, C7

Tissue Specificity: Widely expressed.

Background: This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.

Poids moléculaire: 93 kDa

ID gène: 730

UniProt: P10643

Pathways: Système du Complément