CD44 anticorps (AA 21-259)

N° du produit ABIN5692819

Il existe 11+ publications pour ce produit. L’anticorps anti-CD44 Polyclonal Lapin est utilisé pour la détection de CD44 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS, WB, IHC, IF, ELISA, IHC (fro) et ICC.

Aperçu rapide pour CD44 anticorps (AA 21-259) (ABIN5692819)

Antigène: CD44

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-CD44 anticorps

Épitope: AA 21-259

Fonction: Anti-CD44 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CD44 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human CD44 recombinant protein (Position: Q21-H259).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Immunohistochemistry (Frozen Section), 0.5-1 μg/mL Immunocytochemistry, 0.5-1 μg/mL Immunofluorescence, 2 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CD44 (ABIN5692819)

Wen, Xie, Zhou, Fan, Yu, Chen, Fu, Yan, Guo, Lyu, Kuang, Chai: "The role of combining medroxyprogesterone 17-acetate with human menopausal gonadotropin in mouse ovarian follicular development." dans: Scientific reports, Vol. 8, Issue 1, pp. 4439, (2018) (PubMed).

Zhang, Yan, Liu, Li, Zhang, Pang, Hu, Zhao, Xie, Zhou, Wang, Xie: "Smad3-related miRNAs regulated oncogenic TRIB2 promoter activity to effectively suppress lung adenocarcinoma growth." dans: Cell death & disease, Vol. 7, Issue 12, pp. e2528, (2017) (PubMed).

Ding, Chang, Niu, Dai, Geng, Li, Guo, Xu: "Overexpression of transcription factor Foxa2 and Hnf1α induced rat bone mesenchymal stem cells into hepatocytes." dans: Cytotechnology, Vol. 68, Issue 5, pp. 2037-47, (2016) (PubMed).

Zhang, Shang, Hao, Zheng, Li, Liang, Cui, Liu: "Effects of human umbilical cord mesenchymal stem cell transplantation combined with minimally invasive hematoma aspiration on intracerebral hemorrhage in rats." dans: American journal of translational research, Vol. 7, Issue 11, pp. 2176-86, (2016) (PubMed).

Zhang, Wang, Dai, Cai, Zhan, Gang, Hu, Xia, Zhang: "Lentivirus-mediated PLCγ1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma." dans: Oncotarget, Vol. 7, Issue 7, pp. 8043-54, (2016) (PubMed).

Yin, Zhou, Wang, Ma, Li, Wang, She, Li: "CD44 promotes the migration of bone marrow-derived mesenchymal stem cells toward glioma." dans: Oncology letters, Vol. 11, Issue 4, pp. 2353-2358, (2016) (PubMed).

Yuan, Liu, Li, Li, Sun, Xu, Man, Fu: "Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3957-65, (2015) (PubMed).

Fu, Lv, Zhuang, Chen, Lv, Li, Wang: "An effective inducer of dopaminergic neuron-like differentiation." dans: Neural regeneration research, Vol. 8, Issue 5, pp. 427-34, (2014) (PubMed).

Lin, Li, Han, Li, Lu, Bai, Chen: "Folium Sennae protects against hydroxyl radical-induced DNA damage via antioxidant mechanism: an in vitro study." dans: Botanical studies, Vol. 55, Issue 1, pp. 16, (2014) (PubMed).

Dai, Li, Zhou, Chen, Chen, Xiao: "Genistein promotion of osteogenic differentiation through BMP2/SMAD5/RUNX2 signaling." dans: International journal of biological sciences, Vol. 9, Issue 10, pp. 1089-98, (2013) (PubMed).

Li, Yi, Wu: "Suspension culture combined with chemotherapeutic agents for sorting of breast cancer stem cells." dans: BMC cancer, Vol. 8, pp. 135, (2008) (PubMed).

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet:

Background: CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Gene Full Name: CD44 Molecule (IN blood group)

Poids moléculaire: 82 kDa

ID gène: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling